[Exceptions: prix, faux = silent]

In English orthography, ⟨x⟩ is typically pronounced as the voiceless consonant cluster /ks/ when it follows the stressed vowel (e.g. ox), and the voiced consonant /ɡz/ when it precedes the stressed vowel (e.g. exam). It is also pronounced /ɡz/ when it precedes a silent ⟨h⟩ and a stressed vowel (e.g. exhaust).^[2] Before ⟨i⟩ or ⟨u⟩, it can be pronounced /kʃ/ or /ɡʒ/ (e.g. sexual and luxury); these result from earlier /ksj/ and /ɡzj/. It also makes the sound /kʃ/ in words ending in -xion (typically used only in British-based spellings of the language; American spellings tend to use -ction). When ⟨x⟩ ends a word, it is always /ks/ (e.g. ax), except in loan words such as faux (see French, below).

There are very few English words that start with ⟨x⟩ (the fewest number of any letter). When ⟨x⟩ does start a word, it is usually pronounced /z/ (e.g. xylophone, xenophobia, and xanthan); in rare recent loanwords or foreign proper names, it can also be pronounced /s/ (e.g. the obsolete Vietnamese monetary unit xu) or /ʃ/ (e.g. Chinese names starting with Xi like Xiaomi or Xinjiang). Many of the words that start with ⟨x⟩ are of Greek origin, or standardized trademarks (Xerox) or acronyms (XC). In abbreviations, it can represent "trans-" (e.g. XMIT for transmit, XFER for transfer), "cross-" (e.g. X-ing for crossing, XREF for cross-reference), "Christ-" as shorthand for the labarum (e.g. Xmas for Christmas, Xian for Christian), the "crys-" in crystal (XTAL), or various words starting with "ex-" (e.g. XL for extra large, XOR for exclusive-or).